The Skinny on Ozempic: Potential Drawbacks of Using Ozempic for Weight Loss
Understanding Ozempic: a Type 2 Diabetes Medication
Ozempic, a diabetes medication, has gained popularity as a "weight loss injection" among celebrities like Oprah Winfrey, Kathy Bates, and Elon Musk. But before you jump on the bandwagon, it's crucial to understand the potential downsides of using it for weight loss. Two diabetologists share their insights with ntv.de.
What's the Difference between Ozempic and Wegovy?
In Germany and the EU, Ozempic is approved only for diabetes treatment. For severe weight loss in the case of obesity, Wegovy (with the same active ingredient) is used instead.
Suppressed Appetite and Weight Loss
Ozempic contains semaglutide, a hormone mimic that promotes feelings of fullness and slows down digestion. This reduces food intake and leads to weight loss. The medication is generally free of side effects, according to Jochen Seufert, a diabetologist at the University Hospital Freiburg.
Common Side Effects
Gastrointestinal issues such as nausea, vomiting, diarrhea, heartburn, and stomach pain are possible side effects, which may subside as the body adjusts. Precise dosing can help minimize these side effects [1][3][4].
More Serious Side Effects
- Thyroid and Pancreatic Cancer: While concerns exist about the increased risk of thyroid and pancreatic cancer, studies suggest it is in the promille range or negligible [1].
- Pancreatitis: Rare cases of pancreatitis may occur, but this risk is low [1].
Misuse and Side Effects
Misuse of Ozempic, such as use by people of normal weight who aren't diabetic, can lead to weight loss, underweight, and unwanted side effects. The so-called "Ozempic face" (sunken cheeks, hollow eyes, wrinkles) is a rare occurrence in clinical practice, but it may result from misuse [2].
Overuse and Secondary Diseases
Obesity can lead to secondary diseases such as diabetes, sleep apnea, arthritis, high blood pressure, and increased stroke risk. Jürgen Wagner, a diabetologist at the Stauffenburg Clinic, argues that semaglutides should be used more often in treating obesity to combat these secondary diseases.
Pregnancy and Fertility
Weight loss can increase fertility when people lose weight, regardless of the use of semaglutid. There have been cases where the medication may reduce the effectiveness of birth control pills [2].
Cost and Long-Term Use
Ozempic can be costly, and long-term use should entail sustained lifestyle changes to maintain weight loss once the medication is discontinued [4].
Dental and Oral Health
Reduced saliva production due to the medication may cause dry mouth and potentially long-term damage to oral health [2].
The Bottom Line
Ozempic can help with weight loss when used for the treatment of diabetes, but it's essential to be aware of potential side effects and to consult with healthcare providers to ensure safe use.
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Potential Side Effects and Disadvantages of Using Ozempic for Weight Loss
While Ozempic is not FDA-approved for weight loss, it is often used off-label for this purpose due to its effectiveness in reducing appetite and promoting weight reduction. However, there are several potential side effects and disadvantages associated with its use for weight loss beyond its approved use for diabetes treatment:
Common Side Effects
- Gastrointestinal Issues: Common side effects include nausea, vomiting, diarrhea, stomach pain, and constipation. These symptoms are often mild to moderate and may subside as the body adjusts.
- Facial Changes: There have been reports of "Ozempic face," characterized by a sunken or hollow appearance, increased signs of aging, and facial volume loss. This is a rare occurrence and often a result of misuse.
Less Common but Serious Side Effects
- Pancreatitis: A rare but serious risk associated with Ozempic and other GLP-1 receptor agonists.
- Kidney Problems: There is a risk of acute kidney injury, although this is uncommon.
- Gallbladder Issues: Use of Ozempic has been linked to acute gallbladder disease.
Other Disadvantages
- Cost: Ozempic can be expensive, especially if not covered by insurance.
- Long-Term Use and Weight Regain: Weight loss achieved with Ozempic may be reversible if the medication is stopped, emphasizing the need for sustained lifestyle changes.
- Dental and Oral Health Concerns: Reduced saliva production can lead to dry mouth and potentially lasting damage to oral health.
Overall, while Ozempic can be effective for weight loss, users should be aware of these potential side effects and consult with healthcare providers to manage risks and ensure safe use.
• The use of medicines like Ozempic for weight management is linked to various side effects, such as gastrointestinal issues, facial changes, pancreatitis, kidney problems, gallbladder issues, and dental and oral health concerns.• In the realm of health-and-wellness and weight-management, it's crucial to acknowledge that while medications like Ozempic can aid in weight loss, they often necessitate awareness of potential side effects and consultation with healthcare providers to ensure safe use.
