Scientists ID Lifestyle Factors to Lower Alzheimer's Risk
Scientists have identified several factors that may influence the risk of developing Alzheimer's disease. While some are non-modifiable, such as age and genes, others can be altered through lifestyle changes.
Alzheimer's is a progressive brain disorder that affects memory, thinking, and behaviour. Its exact causes remain unknown, but research suggests a mix of genetic, lifestyle, and environmental factors play a role. Non-modifiable risks include age, sex, genes, family history, and certain brain abnormalities like protein plaques and tangles. Women are particularly vulnerable, with a 20% chance of developing the disease by age 65.
The APOE-e4 gene is the most common genetic risk factor, increasing likelihood when combined with family history. However, lifestyle factors can also impact risk. Head trauma, smoking, high blood pressure, obesity, physical and mental inactivity, and poor diet may all contribute to the disease. Conversely, a heart-healthy diet like the DASH or Mediterranean diet may lower risk. Other factors being studied include brain inflammation, vascular disorders, and gut flora.
While the exact causes of Alzheimer's remain unclear, understanding and addressing modifiable risk factors can help lower the chances of developing the disease. Further research is needed to fully understand the complex interplay of these factors and to develop effective prevention strategies.
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