Potential implications of Xofluza usage: Understanding adverse effects and coping strategies
Xofluza, an antiviral drug, is prescribed short term to help prevent or treat flu. It's available in oral tablet and oral liquid suspension forms. However, it's important to note that Xofluza may not be the right treatment for everyone, especially those with certain medical conditions or factors affecting their health.
In clinical trials, the most common side effects reported in children were vomiting and diarrhea. Mild side effects that have been reported with Xofluza include bronchitis, sinusitis, nausea, diarrhea, headache, and mild allergic reaction.
While these side effects are usually temporary, lasting only a few days, there are less common adverse effects that may not be fully detailed in the official prescribing information. Postmarketing experience has revealed very rare hypersensitivity reactions such as anaphylaxis and angioedema, which are immune-related and may not appear in initial clinical trial data due to their rarity. Clinical trials and observational data report urticaria as an uncommon skin reaction. Symptoms like headache, bronchitis (including tight airways), sinus problems, and diarrhea have been noted during trials, but are less frequent compared to common side effects like nausea and cough.
For mild symptoms of an allergic reaction, call your doctor right away. If diarrhea is bothersome or severe while taking Xofluza, let your doctor know. In such cases, over-the-counter medications like Imodium (loperamide) or Pepto Bismol can be used to manage symptoms.
Xofluza is not known to cause long-term side effects. However, it's important to drink enough fluid to avoid dehydration from diarrhea. Your doctor may suggest avoiding alcohol consumption while you have the flu.
It's crucial to discuss your health history with your doctor before taking Xofluza. If you're pregnant, breastfeeding, or planning for either, talk with your doctor about what flu treatments they recommend. Xofluza may cause an allergic reaction in some people, although it wasn't reported in clinical trials.
While Xofluza and Tamiflu share some similar side effects, they also have some different side effects. For instance, Xofluza may potentially cause hallucinations, although this side effect was not reported in clinical trials.
It's not known whether it's safe to take Xofluza during pregnancy or while breastfeeding. If you'd like to learn more about Xofluza, talk with your doctor or pharmacist.
Remember, if your symptoms are serious and you think you're having a medical emergency, immediately call 911 or your local emergency number.
[1] Drug Safety Communication: FDA warns about rare cases of severe skin reactions with Xofluza (baloxavir marboxil) (US Food and Drug Administration) [2] Baloxavir marboxil (Xofluza): MedlinePlus Drug Information [3] Baloxavir Marboxil (Xofluza): Prescribing Information (Genentech, Inc.) [4] Baloxavir Marboxil (Xofluza): Summary of Product Characteristics (European Medicines Agency)
- Xofluza, an antiviral drug, may cause rare hypersensitivity reactions such as anaphylaxis and angioedema, but these are usually temporary and not detailed in the official prescribing information.
- Some mild side effects of Xofluza include bronchitis, sinusitis, nausea, diarrhea, headache, and mild allergic reactions, while vomiting and diarrhea are the most common side effects in children.
- If diarrhea is bothersome while taking Xofluza, over-the-counter medications like Imodium (loperamide) or Pepto Bismol can be used to manage symptoms.
- It's important to discuss medical conditions and health history with a doctor before taking Xofluza, especially for pregnant women, breastfeeding mothers, or those planning to become pregnant, due to potential uncertainties about its safety during pregnancy and breastfeeding.
