Oral Levetiracetam: Adverse Effects, Applications, Dosage, and Additional Information
Levetiracetam is a widely used anti-epileptic drug (AED) approved by the Food and Drug Administration (FDA) to treat certain types of epilepsy (seizure disorders) in adults and some children. This medication, available as both immediate-release and extended-release oral tablets, is marketed under the brand names Keppra and Keppra XR, respectively.
Uses of Levetiracetam
Levetiracetam is primarily used for partial onset seizures, myoclonic seizures, and generalized tonic-clonic seizures. It is preferred by many clinicians, particularly for generalized motor seizures, and can be used as monotherapy or adjunctive therapy.
Dosages of Levetiracetam
The dosage for Levetiracetam varies based on the specific condition, age, and weight of the patient. For partial-onset seizures in children as young as one month old, the dosage is determined by age and weight in kilograms. The dosage for myoclonic seizures in children ages 12 years and older who have juvenile myoclonic epilepsy is the same as the adult dosage.
For adults, the dosage for partial-onset seizures starts at 500 mg or 1,000 mg, with potential increases every two weeks, up to a maximum dose of 3,000 mg, taken twice daily. For generalized tonic-clonic seizures, the starting dose is 500 mg, with potential increases every two weeks, up to a recommended dose of 1,500 mg, also taken twice daily.
Levetiracetam ER oral tablets, which release the active drug slowly over time, are FDA-approved to treat partial-onset seizures in children ages 12 years and older who weigh 50 kg or more, with the dosage the same as the adult dosage for this use. They are also approved for use in adults and children ages 12 years and older.
Side Effects of Levetiracetam
Common side effects of Levetiracetam include somnolence (feeling sleepy), weakness, increased risk of infection, dizziness, irritability, fatigue, nasal congestion, not feeling as hungry as usual, mild allergic reaction, behavior changes, new or worsening depression, severe skin reactions, difficulties with coordination, withdrawal seizures, and severe allergic reaction.
It is important to note that while serious side effects from Levetiracetam aren't common, they can occur. If you experience serious side effects, call your doctor right away.
Important Considerations
If you or someone you know is in crisis and considering suicide or self-harm, please seek support: Call or text the 988 Lifeline at 988 or chat at 988lifeline.org, text HOME to the Crisis Text Line at 741741, or call 911 or your local emergency services number if you feel safe to do so.
Before starting treatment with Levetiracetam, it is essential to discuss your treatment options with your doctor. They can tell you if Keppra or Keppra XR is a suitable option for you and whether your insurance will cover it.
Comparing Generics and Brand-Name Drugs
If you're interested in learning more about how generics compare with brand-name drugs, see this article.
In summary, Levetiracetam is a broad-spectrum AED with monotherapy use for certain conditions, while Lamotrigine and Brivaracetam have their unique uses and side effect profiles. It's crucial to discuss your treatment options with your healthcare provider to make an informed decision about your care.
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