New Test Detects Wide Range of Carbapenemases, Including Less Common Types
A new test has been developed that can detect a wider range of carbapenemases, the enzymes that make bacteria resistant to carbapenem antibiotics. This includes less common types aside from the frequent OXA-48, KPC, and NDM. The speed test, based on Taqman real-time PCR, can identify multiple carbapenemases in a single reaction from gram-negative bacteria.
The speed test, designed for use in Germany, can detect various OXA variants, not just the common OXA-48. It also picks up less prevalent types other than the main three (OXA-48, KPC, NDM). This is significant as it provides a more comprehensive understanding of carbapenem resistance in the country.
In the United States, the common app can identify both KPC and NDM carbapenemases, which are common there. The procedure targets the bla and bla genes responsible for carbapenem resistance, making it a powerful tool for detecting these enzymes in gram-negative bacteria.
This new speedtest expands the detection of carbapenemases to include less common types, providing a more detailed picture of carbapenem resistance. It is a valuable addition to the fight against antibiotic-resistant bacteria, particularly in Germany and the United States.
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