Large-scale manufacture of human lactoferrin: Helaina amplifies production capacity
Helaina, a leading biotech company, is revolutionising the health and wellness industry with its innovative product, effera lactoferrin. This groundbreaking ingredient is not just about replacing bovine lactoferrin, but about creating a new category and opportunity in the market.
The company is focusing on creating ingredients with real clinical differentiation, drawing inspiration from what the body has perfected in human milk. By producing human lactoferrin through precision fermentation, Helaina aims to target the women's health, active nutrition, and digestive wellness markets.
Superior Body Tolerance, Allergenicity, and Efficacy
The advantages of human lactoferrin produced by Helaina over bovine lactoferrin are significant. In terms of body tolerance, Helaina’s human lactoferrin does not trigger the body to produce antibodies against it, indicating better immune tolerance. This is in contrast to bovine lactoferrin, which is recognized as foreign by the human body and can lead to antibody production, reducing its effectiveness because it is cleared more quickly from the system.
Bovine lactoferrin is also considered an allergen and may provoke allergic reactions, whereas human lactoferrin, being identical to what the body naturally produces, is less likely to cause allergenic responses.
In terms of efficacy, human lactoferrin from Helaina shows superior bioequivalence, remaining in the body longer and delivering enhanced benefits. This translates to better performance in key functions such as iron absorption, immune resilience, and gut health, compared to bovine lactoferrin, which differs structurally and functionally from the human protein.
Sustainable and Scalable Production
Precision fermentation is more sustainable and scalable, offering a consistent and economically viable alternative to bovine lactoferrin which is scarce and expensive to purify from cow’s milk. Helaina has scaled up production capacity for effera lactoferrin to the scale of metric tons.
Clinical Data and Partnerships
The clinical data for effera lactoferrin suggests potential claims for optimising iron utilisation, healthy gut function, healthy inflammatory response, and maintaining a healthy immune system. Helaina continues to work on scaling up production capacity for effera lactoferrin to the scale of metric tons.
Helaina has struck deals with multiple commercial partners who have launched with effera, including Kroma Wellness (SuperCore), Levelle, Healthgevity, Kepos (TryKepos), Young Gut Ultra by Joel Greene, and more. The company is starting to focus more on partnerships, especially for new molecules and ingredients.
Future Launches and Innovations
Additional launches of effera are planned for later this year. Kroma Wellness has developed a product combining effera lactoferrin with other precision-fermented bioactives, including human milk oligosaccharide 2'-FL, and is marketing it as "the first colostrum made for humans."
As people get older, they produce less lactoferrin, and these products are designed to supplement and lift the body to act at its optimal self. Lactoferrin is essential for iron balance, immune function, gut health, and a healthy inflammatory response.
Helaina expresses lactoferrin in a genetically engineered strain of yeast and has self-affirmed the ingredient as GRAS (Generally Recognized as Safe). The company is working with Mitsubishi International Food Ingredients, but details of the partnership cannot be revealed at this stage.
In summary, Helaina’s human lactoferrin is better tolerated by the human body with lower allergenic risk and enhanced functional benefits, making it a premium, clinically differentiated option over bovine lactoferrin.
- Helaina's innovative product, effera lactoferrin, is transforming the health and wellness industry.
- Effera lactoferrin aims to replace bovine lactoferrin and create a new category in the market.
- Helaina is focusing on producing human lactoferrin through precision fermentation.
- Human lactoferrin produced by Helaina does not trigger the body to produce antibodies.
- Bovine lactoferrin, in contrast, is recognized as foreign by the human body and can lead to antibody production.
- Human lactoferrin, being identical to what the body naturally produces, is less likely to cause allergenic responses.
- Bovine lactoferrin is considered an allergen and may provoke allergic reactions.
- Human lactoferrin shows superior bioequivalence and remains in the body longer.
- Helaina's human lactoferrin delivers enhanced benefits in iron absorption, immune resilience, and gut health.
- Bovine lactoferrin differs structurally and functionally from the human protein.
- Precision fermentation is more sustainable and scalable than bovine lactoferrin production.
- Helaina has scaled up production capacity for effera lactoferrin to the scale of metric tons.
- The clinical data for effera lactoferrin suggests potential claims for optimizing iron utilization.
- Helaina continues to work on scaling up production capacity for effera lactoferrin.
- Helaina has struck deals with multiple commercial partners who have launched with effera.
- The company is starting to focus more on partnerships, especially for new molecules and ingredients.
- Additional launches of effera are planned for later this year.
- Kroma Wellness has developed a product combining effera lactoferrin with other precision-fermented bioactives.
- This product is marketed as "the first colostrum made for humans."
- As people get older, they produce less lactoferrin, and these products are designed to supplement and lift the body.
- Lactoferrin is essential for iron balance, immune function, gut health, and a healthy inflammatory response.
- Helaina expresses lactoferrin in a genetically engineered strain of yeast.
- Helaina has self-affirmed the ingredient as GRAS (Generally Recognized as Safe).
- Helaina is working with Mitsubishi International Food Ingredients.
- Details of the partnership between Helaina and Mitsubishi cannot be revealed at this stage.
- Helaina's human lactoferrin is a premium, clinically differentiated option over bovine lactoferrin.
- This superior human lactoferrin holds potential for applications in areas like medical conditions, chronic diseases, chronic kidney disease, cancer, respiratory conditions, digestive health, eye-health, hearing, skin-care, therapies and treatments, nutrition, healthy diets, women’s health, menopause, cardiovascular health, the industry, cbd, finance, energy, skin-conditions, retail, entrepreneurship, transportation, leadership, diversity and inclusion, wearables, smart-home-devices, cybersecurity, automotive, small-business, investing, careers, housing-market, personal-finance, banking and insurance, real-estate, commercial, residential, saving, debt-management, gadgets, smartphones, data and cloud computing, budgeting, technology, artificial-intelligence, and renewable energy.
