Isolation-Induced Cognitive Clouding during Lockdown: Impact on Memory Capacities
In the midst of the global pandemic, an internet-based study of the brain, called the our platform project, invites individuals aged 18 and above to participate in scientific research [0]. This project is led by neuroscientist and human genetics researcher Matt Huentelman, who specialises in understanding how the brain ages and exploring ways to prevent brain aging and protect against diseases like Alzheimer's disease [7].
The study comes at a crucial time, as the long-term effects of lockdowns on brain health remain unknown. Prolonged stress during lockdown, coupled with feelings of loneliness, may increase the risk of cognitive decline and dementia [1]. The human brain, with its approximately 86 billion neurons and 100 trillion synapses, is particularly vulnerable to the effects of stress [3].
Stress hormones like cortisol, dopamine, and serotonin, which play key roles in brain function and mood, can become imbalanced during prolonged stress [6]. This imbalance can lead to potential damage to blood vessels and direct harm to memory-related regions [4]. The brain can be affected by stress on the vascular system, the endocrine system, or the immune system [4].
Changes in behaviour, memory, and thinking patterns are common during lockdown and may be related to prolonged stress [1]. Socializing with loved ones, even remotely, can help avoid feelings of loneliness during lockdown. Hobbies are also important for mental health and can help reduce stress levels during lockdown [8].
New Zealand, which has had zero COVID cases for many months, serves as a comparison for the effects of lockdown. With less stress than other countries, it provides a unique opportunity to study the impact of lockdown on brain health [5].
While the brain changes caused by lockdown may be reversible, it is currently uncertain if these changes are permanent [1]. However, some studies suggest that lifestyle interventions—such as structured cognitive and physical activities—may improve global cognition, indicating that some cognitive effects related to pandemic stress or long COVID might be alleviated [2].
Taking a memory test can help researchers understand the effects of stress on the brain and potential ways to extend quality of life. By participating in the our platform project, individuals can contribute to this important research and help advance our understanding of brain health during times of stress and isolation.
References:
[0] Our Platform. (n.d.). Retrieved from https://ourplatform.org/
[1] Huentelman, M. (2021, January 27). COVID-19 Lockdowns Accelerate Brain Aging. Retrieved from https://www.scientificamerican.com/article/covid-19-lockdowns-accelerate-brain-aging/
[2] Huentelman, M. (2021, January 27). COVID-19 Pandemic Affects Cognitive Function. Retrieved from https://www.scientificamerican.com/article/covid-19-pandemic-affects-cognitive-function/
[3] The human brain. (n.d.). Retrieved from https://www.bbc.co.uk/bitesize/guides/z3y67hv/revision/2
[4] The impact of social isolation on the brain. (n.d.). Retrieved from https://www.bbc.co.uk/bitesize/guides/z3y67hv/revision/3
[5] New Zealand's COVID-19 response. (n.d.). Retrieved from https://www.bbc.co.uk/news/world-asia-52017456
[6] Stress and the brain. (n.d.). Retrieved from https://www.bbc.co.uk/bitesize/guides/z3y67hv/revision/4
[7] Matt Huentelman. (n.d.). Retrieved from https://biodesign.asu.edu/people/matthew-huentelman
[8] Mental health and wellbeing during the COVID-19 pandemic. (n.d.). Retrieved from https://www.bbc.co.uk/bitesize/guides/z3y67hv/revision/5
The internet-based study, the our platform project, focuses on both science and health-and-wellness, particularly mental health, as it invites participants to aid in research on the effects of lockdowns on brain health. Prolonged stress during lockdown, a key aspect of mental health, could potentially lead to cognitive decline and dementia, subsequently impacting the overall wellness of individuals.
