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Funding secured by Ultromics for expansive growth in identifying heart failure at a preliminary stage, to the tune of $55 million.

AI cardiology diagnostic leader Ultromics secures $55 million in its Series C financing round.

Early detection of heart failure receives $55M investment from Ultromics for expansion and growth
Early detection of heart failure receives $55M investment from Ultromics for expansion and growth

Funding secured by Ultromics for expansive growth in identifying heart failure at a preliminary stage, to the tune of $55 million.

In a significant move for the healthcare industry, Ultromics, a pioneering company specializing in AI-driven cardiology diagnostics, has secured $55 million in its Series C funding round. The funding was co-led by L&G, Allegis Capital, and Lightrock, with participation from Oxford Science Enterprises, GV, Blue Venture Fund, Oxford University, University of Chicago Medicine, UPMC Enterprises (the innovation, commercialisation, and investment arm of UPMC, University of Pittsburgh Medical Center), and other undisclosed investors.

Victor Westerlind, Managing Director at Allegis Capital, stated that Ultromics is closing a long-standing blind spot in cardiology by bringing AI and cardiology together. This innovative platform makes it easier for physicians to identify high-risk patients earlier, particularly those with Heart Failure with Preserved Ejection Fraction (HFpEF) and cardiac amyloidosis.

The funding will be instrumental in Ultromics' expansion across the US and other key markets, aiming to bring its AI-enhanced diagnostics to hospitals and echo labs that see the highest volume of at-risk patients.

Advantages and Disadvantages of AI-Driven Diagnostics

AI-driven solutions like Ultromics offer several advantages when used for detecting conditions such as HFpEF and cardiac amyloidosis. Enhanced diagnostic accuracy, early detection and risk stratification, consistency and objectivity, workflow efficiency, and integration of multimodal data are some of the key benefits.

However, challenges such as dependence on the quality of input data, limited transparency (the "black box" issue), potential for bias, regulatory and validation challenges, integration challenges, and the risk of over-reliance on AI need to be carefully managed to ensure safe and effective clinical use.

Ultromics' Innovative Solutions

EchoGo, Ultromics' platform, generates real-time probability scores to help cardiologists identify high-risk patients earlier than traditional methods. In 2025, the company launched EchoGo Score, a new feature that adds AI-driven probability scoring to EchoGo Heart Failure.

In a global study of 18 institutions, Ultromics' latest diagnostic model for cardiac amyloidosis outperformed current clinical risk scores while distinguishing disease from similar conditions. This model was published in the European Heart Journal.

In clinical studies, EchoGo improved the detection of HFpEF by 73.6% when compared with standard clinical risk scores. Ultromics' platform also received FDA Breakthrough Device clearance for EchoGo Amyloidosis in late 2024.

Strengthening Ultromics' Foundation

The funding round comes at a time when the adoption of Ultromics' solutions is gaining momentum. Medicare now reimburses both outpatient and inpatient use of EchoGo, strengthening Ultromics' foundation for scaled adoption across USA hospitals.

Westerlind added that when paired with the latest treatment advances, it's a diagnostic win that will help save lives. With the new funding, Ultromics is poised to make significant strides in improving cardiology diagnostics and patient outcomes.

Despite the challenges, the potential benefits of AI-driven diagnostics are undeniable. By addressing these challenges effectively, companies like Ultromics are set to revolutionize the field of cardiology, making early and accurate diagnoses more accessible than ever before.

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