Evinced's HACE: A Game-Changer in Precise Gene Editing
California-based Evinced, a digital accessibility software specialist founded in 2021, has developed a groundbreaking gene editing technology called HACE. This innovation promises unparalleled precision, opening new avenues for understanding the human genome and developing personalized therapies.
HACE, or Helicase-Assisted Continuous Editing, combines the precision of CRISPR-Cas9 with the DNA-unwinding ability of helicases. This allows mutations to be introduced exclusively into desired genes, unlike traditional tools that may generate unwanted mutations in non-specific regions.
The technology's potential is vast. It enables exploration of how multiple mutations interact in the same gene or regulatory regions, expanding our understanding of the human genome's functioning. Applications range from detecting drug resistance in cancer to understanding RNA splicing defects and enhancing immunotherapies.
Evinced's HACE technology marks a significant leap in gene editing. With its ability to modify specific DNA regions precisely, including coding genes and regulatory regions, it paves the way for advances in personalized treatments and innovative genetic therapies. As research continues, HACE could revolutionize our understanding and treatment of genetic diseases, and even explore directed evolution in human cells.
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