Entresto Dosage Guide: Formulations, Strengths, Administration, and Additional Information
News Article: Entresto for Children with Heart Failure
Entresto, a medication used to treat heart failure in adults, has also been approved for use in children aged one year and older. The medication, which contains sacubitril and valsartan, is available as oral tablets in three strengths: 24/26 mg, 49/51 mg, and 97/103 mg.
For children weighing 40 kg or more, the dosage of Entresto increases over time based on the child's weight. The recommended dosage range for children, according to the Mayo Clinic, starts at approximately 1.6 mg/kg twice daily, with adjustments made by the doctor as tolerated.
More specifically, for children weighing less than 40 kg, the medication is typically prescribed as a liquid suspension, with the dosage increasing over four weeks. For children weighing between 40 and less than 50 kg, the starting dose is one tablet containing 24 mg sacubitril/26 mg valsartan, which may be increased up to 72 mg sacubitril/78 mg valsartan twice daily. For children weighing 50 kg or more, the starting dose is one tablet containing 49 mg sacubitril/51 mg valsartan, which may be increased up to 97 mg sacubitril/103 mg valsartan twice daily.
It is essential to note that the dosage for children under one year or less than 40 kg is carefully adjusted by the physician using oral liquid or pellet forms based on body weight. Dosage adjustments are usually made every two weeks as tolerated.
Entresto is meant to be a long-term treatment, and it is crucial to follow the dosage that your doctor prescribes. If you have questions about your Entresto dosage, consult your doctor. It is also essential to never change your dosage without your doctor's recommendation.
In case of an Entresto overdose, call your doctor right away or use the America's Poison Centers hotline at 800-222-1222. Entresto comes as an oral tablet and can be taken by swallowing it whole. Always follow the dosage that your doctor prescribes for Entresto.
Entresto is a brand-name prescription medication used to lower cardiovascular risks in adults with heart failure. The Entresto dosage your doctor prescribes will depend on factors such as the type and severity of the condition being treated, age, weight, other medications, and other medical conditions.
References:
[1] Mayo Clinic. (2021). Entresto (Sacubitril/valsartan) for children. Retrieved from https://www.mayoclinic.org/drugs-supplements/entresto-sacubitril-valsartan/dosing/drg-20166839
[3] National Institutes of Health. (2021). Entresto (Sacubitril/valsartan) for children. Retrieved from https://www.nlm.nih.gov/medlineplus/druginfo/meds/a691032.html
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