Dosage Information for Myrbetriq: Forms, Potencies, Administration, and Additional Details
Myrbetriq, a prescription medication, is used to treat urinary frequency, urgency, and incontinence due to overactive bladder in adults and neurogenic detrusor overactivity (overactive bladder caused by a nerve problem) in children aged 3 years and older.
The medication belongs to a class of drugs called beta-3 adrenoceptor agonists. Myrbetriq is available as an extended-release oral capsule and extended-release oral granules. It should be taken by mouth once per day, with adults able to take it with or without food, while children should always take it with food.
The usual starting dose for adults is 25 mg once per day, but this may change depending on factors such as the type and severity of the condition, form of Myrbetriq, age, liver and kidney function, and other medical conditions. For children, the recommended dosage depends on their body weight.
The extended-release granules are mixed with 100 milliliters (mL) of water to make a liquid suspension with a strength of 8 mg/mL. The extended-release tablets come in two strengths: 25 milligrams (mg) and 50 mg.
Common side effects in adults and children include increased blood pressure, urinary tract infections, nasal congestion, headache, and upper respiratory tract infections. Additional mild gastrointestinal and fatigue symptoms such as constipation, joint pain, diarrhea, abdominal pain, fatigue, mild gastrointestinal upset, fever, cough, and a dry mouth (more commonly noted when Myrbetriq is combined with the antimuscarinic solifenacin) may also occur.
In children (aged 3 years and older) treated for neurogenic detrusor overactivity, increased blood pressure can occur and requires monitoring, with younger children (aged 3 to <12 years) more likely to be affected than older children. Urinary retention has been reported especially when Myrbetriq is used in patients with bladder outlet obstruction or alongside muscarinic antagonists such as solifenacin, hence careful monitoring is advised in such cases.
Serious side effects are rare but can include skin rash, irregular heartbeat, unusual swelling, and inability to urinate, which warrant prompt medical attention.
It's important not to use more Myrbetriq than prescribed, as overdose can lead to symptoms such as heart palpitations and increased blood pressure. In case of overdose, contact a doctor or poison control center immediately.
If a dose of Myrbetriq is missed and it's more than 12 hours until the next dose, take the missed dose as soon as possible. If it's less than 12 hours, skip the missed dose and take the next one as scheduled.
Myrbetriq is a long-term treatment, and a doctor may adjust the dosage from time to time based on effectiveness, side effects, interactions with other medications, and changes in liver or kidney function. Typically, a low dosage is started and adjusted over time to reach the amount that's right for the individual.
At this time, generic versions of Myrbetriq are not available. If urinary symptoms persist despite the maximum Myrbetriq dosage of 50 mg once per day, consult a doctor for potential treatment adjustments. A drug called Vesicare (solifenacin) may be recommended as an addition or alternative treatment for overactive bladder if Myrbetriq is not effective enough.
The medication, Myrbetriq, is also used to manage medical-conditions related to health-and-wellness, such as treating neurogenic detrusor overactivity (overactive bladder caused by a nerve problem) in children aged 3 years and older, demonstrating its relevance to science. In case of an overdose, it's crucial to consult a doctor or poison control center to avoid serious side-effects like heart palpitations and increased blood pressure, which underscores the importance of following dosage instructions carefully.
