Cost, impacts, applications, administration, and additional details regarding Voranigo medication.
Taking a straightforward approach, let's dive into the world of Voranigo, a brand-name oral tablet used for certain brain tumors. This medication contains the active ingredient vorasidenib and is a targeted cancer therapy, currently only available as a brand-name medication[1][2].
FDA has specifically approved Voranigo to treat grade 2 astrocytomas and oligodendrogliomas in adults and children ages 12 years and older. These tumors are low-grade, slow-growing gliomas, and Voranigo is used after a biopsy or surgery to remove all or part of the tumor[2].
If you or a loved one find yourself in need of Voranigo, remember it's only available as a brand-name medication. As with any medication, costs can vary depending on your insurance, location, and pharmacy. Financial and insurance assistance programs like ServierONE can provide copay cards to help relieve the financial burden[2].
Before diving into potential side effects, here are some interesting facts about Voranigo:- Drug class: isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor.- Prescription required: Yes.- Controlled substance: No[2].
Now, let's address those side effects. Voranigo can cause mild or severe side effects, with the following lists outlining some of the key side effects:
*Mild side effects* Fatigue* Headache* Nausea* Diarrhea* Constipation* Reduced appetite* Pain or stiffness in your muscles or joints* COVID-19* Decreased white blood cell count* Increased liver enzymes[2].
less than 40 kg (about 88 pounds [lb])
*Note: After the Food and Drug Administration (FDA) approves a drug, they continuously track and review its side effects. Your experiences can help make medications safer for everyone. If you develop a side effect while taking Voranigo, you can share your experience with the FDA via MedWatch or by calling 800-FDA-1088[4].
20 mg once per day
Although rare, severe side effects can also occur. Contact your doctor immediately if you experience serious side effects such as:- Liver problems, with symptoms such as pain in the upper right side of your abdomen, loss of appetite, severe tiredness or weakness, dark urine, jaundice, or seizures[2].
Before popping Voranigo tablets, remember that you should swallow them whole with a glass of water. Avoid crushing, splitting, or chewing the tablets[2].
40 kg or more
For those pondering alternative treatments, there are other brain tumor treatments available that may suit you better. If curious, discuss your treatment options with your healthcare provider[5].
40 mg once per day
If you think you may be pregnant, planning to become pregnant, or breastfeeding while taking Voranigo, consult your doctor. Voranigo can have various effects on pregnancy, fertility, birth control, and breastfeeding[2][6].
Now, you might be wondering how Voranigo works. Voranigo targets grade 2 astrocytomas and oligodendrogliomas that have a specific genetic mutation. This drug inhibits the action of abnormal IDH1 and IDH2 enzymes in brain tumor cells, thereby slowing down the growth of these tumor cells and helping prevent them from growing and getting worse[7].
Stay tuned for a follow-up on Voranigo, where we'll delve deeper into pharmacology, interactions, and more!
[1] https://www.goodrx.com/worst-brand-name-drugs-to-go-generic[2] https://www.healthline.com/health/voranigo[3] https://www.goodrx.com/health-tips/if-you-cant-afford-your-prescription-drugs-what-can-you-do[4] https://www.fda.gov/safety/medwatch-fda-safety-information/how-report-side-effect[5] https://www.cancer.org/treatment/understanding-your-diagnosis/finding-clinical-trials/learning-about-clinical-trials.html[6] https://www.mayoclinic.org/drugs-supplements/voranigo-oral-route/tags-side-effects/tcg-20347095[7] https://www.nccn.org/professionals/physician_gls/pdf/brain_tumor_pa.pdf
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
- Voranigo, an oral tablet used for certain brain tumors, is a targeted cancer therapy approved by the FDA to treat Grade 2 astrocytomas and oligodendrogliomas in adults and children aged 12 years and older.
- This medication, only available as a brand-name drug, can have mild side effects such as fatigue, headache, nausea, diarrhea, constipation, reduced appetite, muscle or joint pain, COVID-19, decreased white blood cell count, and increased liver enzymes.
- Severe side effects, though rare, can include liver problems, loss of appetite, severe tiredness or weakness, dark urine, jaundice, seizures, and other medical conditions that may require immediate medical attention.
- Financial and insurance assistance programs like ServierONE can help alleviate the financial burden associated with Voranigo costs, which can vary depending on insurance, location, and pharmacy.
- Other brain tumor treatments and therapies might be more suitable for some individuals, so discussing treatment options with healthcare providers is essential.
- It is crucial to take Voranigo tablets orally, swallowing them whole with a glass of water, and avoid crushing, splitting, or chewing the tablets.
- To better understand how Voranigo works, it targets brain tumors with a specific genetic mutation, inhibiting the action of abnormal IDH1 and IDH2 enzymes, hence slowing down tumor cell growth.
