Cost, effects, applications, and other details of Voranigo, including dosage guidelines.
Heyo! Let's chat about Voranigo, a pill that fights certain brain tumors. The Food and Drug Administration (FDA) gave the green light for using it on grade 2 astrocytomas and oligodendrogliomas in both adults and children 12 or older. These tumors are part of a group known as gliomas, where 'astrocytes' and 'oligodendrocytes' are the brain cells they originate from, respectively.
Brain tumors come in different grades, with grade 2 being lower, growing slowly, but still spreading into nearby brain tissue. Voranigo is specifically for those having the genetic mutation (whether IDH1 or IDH2) in their cells. The mutation causes problems with certain enzymes that help cells make energy.
Since Voranigo is a brand-name medication, you won't find it in generic form yet. But why bother with generic, right? If you're curious about costs, prices could vary depending on factors like your insurance coverage, location, and the pharmacy you use.
Financial help and insurance assistance programs, like ServierONE, can be a lifesaver. Check them out if you need support or help understanding your insurance coverage. Give them a ring at 800-813-5905 or swing by their website for more details!
Now, don't forget that no medicine is without its side effects. Mild side effects of Voranigo may include fatigue, headaches, nausea, diarrhea, constipation, reduced appetite, muscle or joint pain, COVID-19, decreased white blood cell counts, and increased liver enzymes[2]. If these symptoms feel more severe or persist for too long, reach out to your doctor or pharmacist for tips on how to deal with them.
Serious side effects like liver problems or seizures might happen but are less common. If any of these symptoms occur, call your doc right away. For a full list of side effects and more info, ask your doctor or pharmacist.
less than 40 kg (about 88 pounds [lb])
Voranigo is a targeted cancer therapy that helps stop the tumor from growing. It's usually taken after biopsy or surgery to remove all or part of the tumor[2].
20 mg once per day
If you or someone else accidently takes too much Voranigo, give your doctor a call, or use America's Poison Centers at 800-222-1222 or their online tool. Seek emergency help if symptoms feel life-threatening[2].
When it comes to Voranigo, don't mix it up with certain other medications, supplements, or foods, or alcohol, as it could lead to interactions. Ask your doctor or pharmacist about the safety of those during Voranigo treatment[2].
40 kg or more
If you're planning a pregnancy or already pregnant, talk to your doctor about safer alternatives for treating those brain tumors. During your treatment with Voranigo, you'll need to use nonhormonal birth control to avoid unwanted pregnancies. If you're breastfeeding or want to breastfeed, it's best to avoid Voranigo altogether[2].
40 mg once per day
Before starting Voranigo, share all your other medications, supplements, and vitamins you're taking with your doctor and pharmacist to avoid any potential interactions[2].
Voranigo works by blocking the action of those abnormal enzymes we talked about earlier, helping slow down tumor growth[2].
Here are answers to some popular questions about Voranigo:
- Can Voranigo be used for glioblastoma?No, Voranigo isn't approved for treating glioblastoma. It's meant for grade 2 astrocytomas and oligodendrogliomas, although some glioblastomas may have the same mutation targeted by Voranigo. It hasn't been studied for glioblastoma yet[2].
- Is Voranigo chemotherapy?No, Voranigo isn't chemotherapy. It's actually a targeted cancer therapy that works more selectively on cancer cells[2].
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
If you've got more questions or concerns about Voranigo, chat with your doctor! They'll help you out. But remember, this info doesn't replace professional medical advice. Always consult a healthcare professional for accurate information tailored to your situation.
Good luck, and stay strong, friend!
Enrichment Data:- Voranigo is a brand-name medication with vorsasidenib as an active ingredient, used for treating specific brain tumors, i.e., grade 2 astrocytomas and oligodendrogliomas, in adults and children aged 12 and above.- The reason it is prescribed for these tumors is that they contain a particular genetic mutation (either IDH1 or IDH2), which causes enzymes to function improperly, leading to uncontrolled cell growth.- Voranigo is part of a group of medications known as targeted cancer therapies, specifically the isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitors.- At the moment, there is no generic form of Voranigo available in the United States.- Possible side effects include but are not limited to fatigue, headaches, nausea, diarrhea, constipation, reduced appetite, muscle or joint pain, cough, decreased white blood cell count, and increased liver enzymes.- Serious side effects like liver problems and seizures can occur but are less common. It is essential to seek medical attention if any of these symptoms develop.- Voranigo is taken once daily, and the dose can vary based on factors such as age, body weight, and the occurrence of any side effects.- Voranigo is not indicated for treating glioblastoma, as it has not been studied for that specific type of tumor.- The FDA approves medications for use based on clinical trials, but the side effects and effectiveness may vary in real-world situations, and sharing personal experiences can help make medications safer for everyone.
[1] U.S Food and Drug Administration. (2021, May 14). 2-Hydroxyglutaric acid dehydrogenase (HGD) inhibitors: A review and future perspectives on the treatment of IDH1/IDH2-mutant tumors. https://www.fda.gov/files/drugs/ attempting/2021/May/pdf/2021-05-14-HGD-Inhibitors_Review-and-FuturePerspectives_FINAL.pdf
[2] MedicineNet. (2021, June 9). Voranigo: Uses, Dosage, Side Effects, Interactions, Warnings, and More. https://www.medicinenet.com/voranigo/article.htm
Voranigo, a brand-name medication, specifically targets certain brain tumors like astrocytomas and oligodendrogliomas, which are part of gliomas. This medication is a targeted cancer therapy that works by blocking the action of abnormal enzymes, helping slow down tumor growth.
Since Voranigo is meant for those having the genetic mutation (IDH1 or IDH2) in their cells, it's important to note that it's not approved for treating glioblastoma, a different type of brain tumor.
The dosage for Voranigo varies based on factors such as age and body weight, and it's essential to consult a healthcare professional before starting the treatment to avoid any potential interactions with other medications, supplements, or foods.
while dealing with side effects like fatigue, headaches, nausea, diarrhea, constipation, reduced appetite, muscle or joint pain, COVID-19, decreased white blood cell counts, and increased liver enzymes, it's crucial to reach out to a doctor or pharmacist for tips on how to manage them.
If more serious side effects like liver problems or seizures occur, immediate medical attention should be sought. It's also important to consider that Voranigo isn't yet available in generic form in the United States, so costs may vary depending on factors like insurance coverage, location, and the pharmacy used.
Financial help and insurance assistance programs, like ServierONE, can provide support or help understand insurance coverage, making this life-saving medication more accessible.
