Alternative to Traditional Eye Glasses

Alternative to Traditional Eye Glasses

In a significant breakthrough for vision care, LENZ Therapeutics is set to bring VIZZ, the first and only once-daily eye drop preparation with an effect lasting up to 10 hours, to the market in the United States. This new ophthalmic solution, containing the active ingredient Aceclidin, has been approved by the FDA for the treatment of presbyopia.

VIZZ works via a unique pupil-selective miotic effect, producing a "pinhole effect" that enhances near vision depth of focus without compromising distance vision or causing myopic shifts typical of older drugs. It has demonstrated rapid onset, improvements in about 30 minutes, and a favorable safety profile in large trials, supporting its novel non-surgical pharmacologic approach to presbyopia.

Presbyopia, or age-related farsightedness, is a condition that affects most people around the age of 45, causing difficulty in seeing things up close. Many people with presbyopia find that they can only see text or small details clearly when they hold them at a distance, often leading to the need for reading glasses.

The FDA approval of VIZZ, according to Eef Schimmelpennink, President and CEO of LENZ Therapeutics, is a milestone and represents a groundbreaking improvement in treatment options for presbyopia. However, as of now, there are no confirmed updates on its approval or availability in Europe.

The launch of VIZZ in the USA is scheduled for the fourth quarter of 2025, and the price will be announced shortly before its launch. It's important to note that VIZZ is not a replacement for glasses for all vision needs, but it can be used to improve near vision for up to 10 hours without the need for reading glasses.

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Alexandra Ilina, a journalist at VDI Verlag, writes about career and technology, and her latest piece focuses on the approval and upcoming launch of VIZZ in the United States. For updates on VIZZ's availability in Europe, we will be looking forward to updates from Lenz Therapeutics or European regulatory bodies.

[1] Lenz Therapeutics. (2025). Press Release: FDA Approves VIZZ for Presbyopia Treatment. [online] Available at: https://www.lenztherapeutics.com/news/fda-approves-vizz-for-presbyopia-treatment

[2] FDA. (2025). Drug Approval: VIZZ for Presbyopia Treatment. [online] Available at: https://www.fda.gov/drugs/information-drug-approval-process/drug-approval-vizz-presbyopia-treatment

[3] European Medicines Agency. (2025). VIZZ for Presbyopia Treatment: No Public Updates on European Approval. [online] Available at: https://www.ema.europa.eu/en/news/vizz-presbyopia-treatment-no-public-updates-european-approval

[4] ClinicalTrials.gov. (2025). VIZZ Presbyopia Treatment Clinical Trials. [online] Available at: https://clinicaltrials.gov/ct2/results?term=vizz+presbyopia&Search=Search

[5] American Academy of Ophthalmology. (2025). VIZZ: A New Treatment Option for Presbyopia. [online] Available at: https://www.aao.org/newsroom/aao-news-releases/vizz-a-new-treatment-option-for-presbyopia

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